Iterum Therapeutics plc is a clinical-stage pharmaceutical company. The Company develops differentiated anti-infectives aimed at combating the global crisis of multi-drug resistant (MDR) pathogens to improve the lives of people affected by serious and life-threatening diseases around the world. The Company is focused on developing and commercializing sulopenem, which is an oral and intravenous penem. Sulopenem is a potent, thiopenem antibiotic delivered intravenously, which is active against bacteria that belong to the group of organisms known as gram-negatives and cause urinary tract and intra-abdominal infections. It is also developed sulopenem in an oral tablet formulation, sulopenem etzadroxil-probenecid. Sulopenem has demonstrated potent in vitro activity against all genera of Enterobacteriacease, in anaerobes, such as Bacteroides, Prevotella, Porphyromonas, Fusobacterium and Peptostreptococcus, gram-positive organisms, including methicillin-susceptible staphylococci, and others.