(Reuters) - Wall Street's main indexes opened lower on Wednesday, a day after the Nasdaq scaled a fresh peak, as investors assessed the risk to the domestic economy from a surge in coronavirus cases in several U.S. states.
The Dow Jones Industrial Average (DJI) fell 163.14 points, or 0.62%, at the open to 25,992.96. The S&P 500 (SPX) opened lower by 16.89 points, or 0.54%, at 3,114.40. The Nasdaq Composite (IXIC) fell 37.55 points, or 0.37%, at 10,093.82 shortly after market open.