Agios Pharmaceuticals, Inc., a biopharmaceutical company, discovers and develops medicines in the field of cellular metabolism in the United States. Its lead product includes PYRUKYND (mitapivat), an activator of wild-type and mutant pyruvate kinase (PK), enzymes used for the treatment of hemolytic anemias in adults with PK deficiency. The company’s PYRUKYND product also used for the treatment of sickle cell disease that is in phase 3 clinical trial; for the treatment of PK deficiency in pediatric patients; and for the treatment of adult patients with non-transfusion dependent and transfusion-dependent alpha- or beta-thalassemia. In addition, it develops tebapivat, a PK activator for the treatment of lower-risk myelodysplastic syndrome and hemolytic anemias; AG-181, a phenylalanine hydroxylase stabilizer for the treatment of phenylketonuria (PKU); and AG-236, an siRNA in-licensed from Alnylam, targeting the transmembrane serine protease 6 (TMPRSS6) gene for the treatment of polycythemia vera. Agios Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.
Pyrukynd's Promise | Explore Agios's lead drug candidate Pyrukynd, potentially the next treatment for thalassemia and sickle cell disease, awaiting FDA decision by September 2025 |
Financial Fortitude | With $1.4 billion in cash and a robust financial health score, Agios stands well-positioned to fund its ambitious drug development pipeline |
Market Dynamics | Delve into Agios's competitive landscape, including challenges from Novo Nordisk's etavopivat and emerging liver safety signals for Pyrukynd |
Analyst Outlook | Analyst price targets range from $38 to $71, with an average of $56.25, suggesting potential upside from the current $30.11 trading price |
Metrics to compare | AGIO | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipAGIOPeersSector | |
|---|---|---|---|---|
P/E Ratio | −4.0x | −2.4x | −0.6x | |
PEG Ratio | 0.02 | 0.05 | 0.00 | |
Price/Book | 1.2x | 4.0x | 2.6x | |
Price / LTM Sales | 35.4x | 9.4x | 3.4x | |
Upside (Analyst Target) | 34.2% | 247.2% | 39.6% | |
Fair Value Upside | Unlock | 11.4% | 5.2% | Unlock |