Breaking News

Aileron Therapeutics Inc (ALRN)

NASDAQ

Add to/Remove from a Portfolio Add to Watchlist

4.5500 -0.3700 -7.52%

16:00:01 - Closed. Currency in USD ( Disclaimer )

After Hours

4.5500

-0.0000

-0.0000%

16:22:54 - Real-time Data

Volume: 318,934
Bid/Ask: 4.4500 / 4.8500
Day's Range: 4.4700 - 5.0000

Type: Equity

Market: United States

Aileron Therapeutics Inc Company Profile

Get an in-depth profile of Aileron Therapeutics Inc, including a general overview of the company's business and key management, as well as employee data and location and contact information.

IndustryBiotechnology & Medical Research

SectorHealthcare

Employees

Equity Type

ORD

Aileron Therapeutics, Inc. is a clinical-stage chemoprotection oncology company. It is focused on developing medicines to make chemotherapy safer. Its ALRN-6924 product is a MDM2/MDMX dual inhibitor that leverages its peptide drug technology, which is designed to activate p53, which in turn upregulates p21, a known inhibitor of the cell replication cycle. ALRN-6924 is the chemoprotective agent in clinical development, which focused on treating patients with p53-mutated cancers. It is developing ALRN-6924 to selectively protect healthy cells in patients with cancers that harbor p53 mutations to reduce or eliminate chemotherapy-induced side effects without interrupting chemotherapy’s destruction of cancer cells. It stabilizes peptides by stapling them with hydrocarbon bonds into their natural alpha-helical conformation. ALRN-6924 can pause cell division in cells with wild type, p53, include normal bone marrow cells and ALRN-6924 has no activity against cancer cells with mutations in p53.

Contact Information

Address 285 Summer Street Suite 101
Boston, 02210
United States

Phone 617 995 0900

Fax 617 995 2410

Web www.aileronrx.com

Top Executives

Name	Age	Since	Title
Reinhard J. Ambros	69	2013	Independent Lead Director
William Carl Fairey	59	2023	Independent Director
Josef H. von Rickenbach	69	2019	Independent Chairman
Alan A. Musso	62	2023	Independent Director
Manuel C. Aivado	54	2014	Director
Alan F. List	69	2018	Member of Scientific Advisory Board
Carol L. Prives	-	2018	Member of Scientific Advisory Board
Ulrich Steidl	-	-	Member of Scientific Advisory Board
Brian J. Druker	69	2018	Member of Scientific Advisory Board
James Brian Windsor	57	2023	CEO & Director

We encourage you to use comments to engage with users, share your perspective and ask questions of authors and each other. However, in order to maintain the high level of discourse we’ve all come to value and expect, please keep the following criteria in mind:

Enrich the conversation
Stay focused and on track. Only post material that’s relevant to the topic being discussed.
Be respectful. Even negative opinions can be framed positively and diplomatically.
Use standard writing style. Include punctuation and upper and lower cases.
NOTE: Spam and/or promotional messages and links within a comment will be removed
Avoid profanity, slander or personal attacks directed at an author or another user.
Don’t Monopolize the Conversation. We appreciate passion and conviction, but we also believe strongly in giving everyone a chance to air their thoughts. Therefore, in addition to civil interaction, we expect commenters to offer their opinions succinctly and thoughtfully, but not so repeatedly that others are annoyed or offended. If we receive complaints about individuals who take over a thread or forum, we reserve the right to ban them from the site, without recourse.
Only English comments will be allowed.

Perpetrators of spam or abuse will be deleted from the site and prohibited from future registration at Investing.com’s discretion.

I have read and understood Investing.com Canada's comment guidelines and agree to the terms described.

I Agree

ALRN Comments

Write your thoughts about Aileron Therapeutics Inc

Are you sure you want to delete this chart?

Delete Cancel

Post

Post also to:

Replace the attached chart with a new chart ?

Replace Cancel

1000

Comment Guidelines

Your ability to comment is currently suspended due to negative user reports. Your status will be reviewed by our moderators.

Please wait a minute before you try to comment again.

Thanks for your comment. Please note that all comments are pending until approved by our moderators. It may therefore take some time before it appears on our website.

Donald Wilson Feb 01, 2021 11:21

Follow this post

Unfollow this post

Save

Saved. See Saved Items.

This comment has already been saved in your Saved Items

Block User

Does anyone have any idea what is driving this down 8% today?

0 0

Report

<div id="comment">
				<div class="comment js-comment" data-comment-id="{commentID}" id="comment-{commentID}" data-user-id="200375537">
    <div class="mainComment js-content">
       <div class="commentInnerWrapper">
        <a href="{userLink}" class="js-user-link"><img src="{userImage}" width="33" height="33" alt="{usernameAlt}" class="img" onerror="this.src='https://i-invdn-com.investing.com/defaultUserMaleTmp.png';"></a><div class="commentBody">
                					<span class="commentUsername">
                    	<a href="{userLink}" class="js-user-link js-user-name">{username}</a>
					</span>
                                <span class="js-date" comment-date="{dateFormat}" comment-date-formatted="{dateFormatted}" title="{dateTitle}">Just Now</span>
                <div class="commentDropDown js-commentDropDownWrapper " data-user-id="200375537" data-cid="{commentID}">
	<a href="javascript:void(0);" class="threeDotsIconSmall js-thinDropdownArrow"></a>
	<div class="tooltipPopup commentActionsPop noHeader js-commentDropDownOptions displayNone">
		<div class="addRow js-option share">
			<a href="javascript:void(0);" class="js-commentSharePopup" data-cid="{commentID}" data-curl="{commentLink}"><span class="smallShareIcon middle"></span>Share</a>
		</div>

<div class="js-option addRow follow">
            <div class="js-follow-post-button" data-reg_ep="follow comment">
                <span class="alertfollowIcon middle"></span>Follow this post            </div>
            <div class="js-unfollow-post-button displayNoneImp">
                <span class="alertUnfollowIcon middle"></span>Unfollow this post            </div>
        </div>

<div class="addRow js-option save"  data-reg_ep="save comment">
		<a href="javascript:void(0);" class="js-save-item-btn" data-item-type="comments" data-item-id="{commentID}">
			<i class="saveItemBigIcon middle"></i>
			Save		</a>
	</div>
	<div class="addRow saveItemsConfirmation noHover displayNone js-saveItemResult">
		
<div class="content js-saveItemSuccess displayNone">
	<span class="mediumGreenSuccessIcon"></span><span>Saved. See <a href="/members-admin/saved-items" target="_blank">Saved Items</a>.</span>
	<a href="javascript:void(0);" class="bugCloseIcon js-close"></a>
</div>
<div class="content js-saveItemAlreadySaved saveItemAlreadySaved displayNoneImp">
	<span>This comment has already been saved in your <a href="/members-admin/saved-items" target="_blank">Saved Items</a></span>
	<a href="javascript:void(0);" class="bugCloseIcon js-close"></a>
</div>
	</div>

<div class="addRow js-option blockUser js-block-option" data-comment-id="{commentID}"  data-user-id="200375537" data-reg_ep="block user comments">
			<a href="javascript:void(0);">
				<span class="blockIcon middle"></span>Block User			</a>
		</div>
				<div class="addRow shareButtons js-sharePopup displayNone">
			<div class="js-shareComment"><span class="js-shareCommentSpan"></span></div>
		</div>
	</div>
</div>
                 <div class="commentAuthor js-comment-by-author"><span class="commentAuthorIcon"></span>Author's response</div>             </div>
		<div id="commentText-{commentID}" class="js-text-wrapper commentText withImage">
							<div id="commentBigChart{commentID}" class="commentBigChart js-comment-chart" onclick="openViewChartPopup('{commentID}')">
					<img src="https://d68-invdn-com.investing.com/comments_images/{commentImage}" alt="{commentAlt}">
					<i class="newMagnifyChartIcon"></i>
				</div>
						<span class="js-text">{commentContent}</span>
			<div class="clear"></div>
							<div class="commentButtons js-not-master-user">
					<a href="javascript:void(0)" class="reply js-reply-btn" data-real-parent-id="{commentID}" data-to-user-name="{username}" data-to-user-id="200375537">Reply</a>
					<div class="inlineblock likeDislikeBox js-like-dislike-box" data-item-id="{commentID}">
	<input class="js-like-checkbox" type="checkbox" name="option" value="Yes" id="like_{commentID}">
	<label for="like_{commentID}" class="like" title="I agree"></label>
	<span class="numOfLikes js-like-count lighterGrayFont">0</span>
	<input class="js-dislike-checkbox" type="checkbox" name="option" value="No" id="dislike_{commentID}">
	<label for="dislike_{commentID}" class="dislike" title="I disagree"></label>
	<span class="numOfDislikes js-dislike-count lighterGrayFont">0</span>
</div>

<div class="reportComment js-flag float_lang_base_2">
                            <a href="javascript:void(0);" id="commentFlag_{commentID}">
                                <span class="reportCommentIcon middle"></span><span class="inlineblock middle">Report</span>
                            </a>
                        </div>
                    				</div>
					</div>
	   </div>
	</div>
	</div>			</div>
			<div id="reply">
				
    <div class="commentReply js-comment js-comment-reply" data-comment-id="{commentID}" id="comment-{commentID}" data-user-id="">
		<div class="commentInnerWrapper"><a href="{userLink}" class="js-user-link"><img src="{userImage}" width="33" height="33" alt="{usernameAlt}" class="img" onerror="this.src='https://i-invdn-com.investing.com/defaultUserMaleTmp.png';"></a><div class="commentBody js-content">
            				<span class="commentUsername">
					<a href="{userLink}" class="commentUsername js-user-link js-user-name" onMouseOver="">{username}</a>
				</span>
                        <span class="js-date" comment-date="{dateFormat}" comment-date-formatted="{dateFormatted}" title="{dateTitle}">Just Now</span>
			 <div class="commentAuthor js-comment-by-author"><span class="commentAuthorIcon"></span>Author's response</div> 			<div class="commentDropDown js-commentDropDownWrapper " data-user-id="" data-cid="{commentID}">
	<a href="javascript:void(0);" class="threeDotsIconSmall js-thinDropdownArrow"></a>
	<div class="tooltipPopup commentActionsPop noHeader js-commentDropDownOptions displayNone">
		<div class="addRow js-option share">
			<a href="javascript:void(0);" class="js-commentSharePopup" data-cid="{commentID}" data-curl="{commentLink}"><span class="smallShareIcon middle"></span>Share</a>
		</div>

</div>
		<div id="commentText-{commentID}" class="js-text-wrapper commentText withImage">
							<div id="commentBigChart{commentID}" class="replyBigChart displayNone js-comment-chart">
					<img src="https://d68-invdn-com.investing.com/comments_images/{commentImage}" alt="{commentAlt}">
					<i class="newMagnifyChartIcon"></i>
				</div>
				<span id="commentSmallChart{commentID}" class="commentSmallChart pointer js-comment-chart" onclick="openViewChartPopup('{commentID}')">
                    <img src="https://d68-invdn-com.investing.com/comments_images/{commentImageSmall}" width="116" height="52" alt="{commentAlt}">
                    <span class="chartMagnifyOverlay displayNone"></span>
                    <span class="searchGlassIcon chartMagnify displayNone"></span>
                </span>
						<span class="js-text">{commentContent}</span>
			<div class="clear"></div>
							<div class="commentButtons js-not-master-user">
					<a href="javascript:void(0)" class="reply js-reply-btn" data-real-parent-id="{commentID}" data-to-user-name="{username}" data-to-user-id="">Reply</a>
					<div class="inlineblock likeDislikeBox js-like-dislike-box" data-item-id="{commentID}">
	<input class="js-like-checkbox" type="checkbox" name="option" value="Yes" id="like_{commentID}">
	<label for="like_{commentID}" class="like" title="I agree"></label>
	<span class="numOfLikes js-like-count lighterGrayFont">0</span>
	<input class="js-dislike-checkbox" type="checkbox" name="option" value="No" id="dislike_{commentID}">
	<label for="dislike_{commentID}" class="dislike" title="I disagree"></label>
	<span class="numOfDislikes js-dislike-count lighterGrayFont">0</span>
</div>

Are you sure you want to delete this chart?

Delete Cancel

Post

Replace the attached chart with a new chart ?

Replace Cancel

1000

Comment Guidelines

Your ability to comment is currently suspended due to negative user reports. Your status will be reviewed by our moderators.

Please wait a minute before you try to comment again.

I feel that this comment is:

Spam

Offensive

Thank You!

Your report has been sent to our moderators for review

More Categories

1D1W1M6M1Y5YMax

S&P/TSX	21,714.54	-297.08	-1.35%
S&P/TSX 60	1,301.35	-16.12	-1.22%
US 30	37,798.9	-17.0	-0.05%
US 500	5,025.7	-10.0	-0.20%
S&P 500 VIX	15.65	+0.98	+6.68%
DAX	17,921.95	-196.37	-1.08%
Dollar Index	106.205	+0.757	+0.72%

Crude Oil WTI	81.27	-0.21	-0.26%
Brent Oil	85.94	-0.03	-0.03%
Natural Gas	1.954	-0.001	-0.05%
Gold	2,301.70	+4.40	+0.19%
Silver	26.605	+0.035	+0.13%
US Soybeans	1,162.50	-19.50	-1.65%
US Cotton #2	78.49	-3.03	-3.72%

Bombardier Inc	62.720	-0.380	-0.60%
Enbridge	35.56	-0.40	-1.11%
Air Canada	20.32	+0.22	+1.09%
Ovintiv	21.70	-0.39	-1.77%
Apple	170.33	-3.17	-1.83%
Alibaba ADR	74.86	-1.55	-2.04%
Tesla	183.40	-10.65	-5.49%

Canada 5Y	3.901	+0.035	+0.92%
Canada 10Y	3.852	+0.034	+0.88%
Canada 30Y	3.707	+0.029	+0.80%
U.S. 2Y	5.037	+-0.009	+-0.17%
U.S. 10Y	4.678	-0.009	-0.19%
U.S. 30Y	4.784	+-0.005	+-0.11%
Germany 10Y	2.5895	+0.0085	+0.33%

Recent Quotes

	Name	Price	Chg.	Chg. %
	ALRN	4.5500	-0.3700	-7.52%

Market Movers

Name	Last	Chg. %	Vol.
Enbridge	48.95	-0.41%	13.53M
Toronto Dominion Bank	81.67	+0.77%	7.79M
TC Energy	49.32	+0.35%	7.03M
RBC	133.19	-0.61%	4.50M
Shopify Inc	96.65	-2.40%	3.46M
Bank of Montreal	122.97	-0.35%	3.36M
Canadian Pacific Kansas City	108.00	-2.26%	2.32M

Name	Last	Chg. %	Vol.
Irwin Naturals	0.30	+150.00%	2.50K
Nirvana Life Sciences	0.05	+150.00%	3.00K
Lifeist Wellness	0.010	+100.00%	267.00K
Mijem Newcomm Tech	0.01	100.00%	4.00K
Vencanna Ventures	0.0200	+100.00%	463.00K
Divergent Energy Services	0.0100	+100.00%	5.00K
Adex Mining Inc	0.010	+100.00%	1.02M

Name	Last	Chg. %	Vol.
Southern Arc Minerals	0.06	-57.14%	5.00K
Horizonte Minerals	0.0050	-50.00%	12.10K
Global Cannabis Apps	0.010	-50.00%	65.50K
Biome Grow	0.005	-50.00%	10.00K
Plant Veda Foods	0.03	-50.00%	8.40K
Comprehensive Healthcare Systems	0.01	-50.00%	2.00K
Braxia Scientific	0.01	-50.00%	614.00K