Apellis Pharmaceuticals Inc (APLS)

Currency in USD
17.21
-0.76(-4.23%)
Closed·
17.55+0.34(+1.98%)
·
Unusual trading volume
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Fair Value
Day's Range
17.1618.09
52 wk Range
16.1030.48
Key Statistics
Prev. Close
17.97
Open
17.96
Day's Range
17.16-18.09
52 wk Range
16.1-30.48
Volume
5.6M
Average Volume (3m)
2.75M
1-Year Change
-28.7075%
Book Value / Share
2.93
Fair Value
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Fair Value Upside
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APLS Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
33.40
Upside
+94.07%
Members' Sentiments
Bearish
Bullish
ProTips
RSI suggests the stock is in oversold territory
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Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Sell
Technical Indicators
Strong Sell
Moving Averages
Strong Sell

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs. It offers EMPAVELI for the treatment of paroxysmal nocturnal hemoglobinuria; and SYFOVRE for treating geographic atrophy secondary to age-related macular degeneration and geographic atrophy (GA). The company also develops EMPAVELI to treat C3 glomerulopathy and immune complex membranoproliferative glomerulonephritis, focal segmental glomerulosclerosis, and delayed graft function; and APL-3007, a small interfering RNA, or siRNA for the treatment of GA. In addition, it conducts preclinical studies for APL-9099, a treatment targeting the neonatal Fc receptor, or FcRn, which has the potential to be a first-in-class gene editing treatment for future target indications with one-time dosing; and developing other programs with its proprietary in-house capabilities and under its Beam collaboration. It has a collaboration and license agreement with Swedish Orphan Biovitrum AB (publ) for development and commercialization of pegcetacoplan; and a collaboration with Beam Therapeutics, Inc. focused on the use of Beam’s base editing technology to discover new treatments for complement-driven diseases. Apellis Pharmaceuticals, Inc. was incorporated in 2009 and is headquartered in Waltham, Massachusetts.

Employees
736

Apellis Pharmaceuticals Inc Earnings Call Summary for Q4/2025

  • Q4 2025 revenue reached $200M, exceeding forecast of $198.82M; full-year revenue hit $1B including $275M one-time payment.
  • Syfovre generated $155M and Empaveli $35M in Q4; strong product demand continues despite 6.36% pre-market stock decline to $21.04.
  • Operating expenses rose to $251M from $239M year-over-year, driven by new pivotal trials and milestone payments.
  • 2026 guidance projects modestly higher expenses; planned Syfovre prefilled syringe launch and AI-enabled OCT technology development underway.
  • Company managing $94M convertible debt maturing September 2026; maintains strong liquidity with 3.54 current ratio.
Last Updated: 2026-02-24, 09:48 a/m
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Compare APLS to Peers and Sector

Metrics to compare
APLS
Peers
Sector
Relationship
P/E Ratio
98.3x13.2x−0.5x
PEG Ratio
0.890.060.00
Price/Book
5.9x7.0x2.6x
Price / LTM Sales
2.2x6.7x3.1x
Upside (Analyst Target)
71.4%79.2%57.5%
Fair Value Upside
Unlock16.9%8.6%Unlock

Analyst Ratings

15 Buy
7 Hold
1 Sell
Ratings:
23 analysts
Overall Consensus
Buy

Analysts 12-Month Price Target:

Average 33.40
(+94.07% Upside)
Firm
ArticlePositionPrice TargetUpside / DownsideFrom Price TargetActionDate
Cantor Fitzgerald
Buy31.00+80.13%35.00MaintainMar 18, 2026
Mizuho
Hold20.00+16.21%19.00MaintainMar 13, 2026
Roth/MKM
Buy31.00+80.13%-New CoverageMar 13, 2026
Roth/MKM
Buy31.00+80.13%-New CoverageMar 13, 2026
Roth/MKM
Buy31.00+80.13%-New CoverageMar 13, 2026

Earnings

Latest Release
Feb 24, 2026
EPS / Forecast
0.47 / -0.38
Revenue / Forecast
199.91M / 198.82M
EPS Revisions
Last 90 days

APLS Income Statement

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FAQ

What Is the Apellis Pharma (APLS) Stock Price Today?

The Apellis Pharma stock price today is 17.21 USD.

What Stock Exchange Does Apellis Pharma Trade On?

Apellis Pharma is listed and trades on the Nasdaq Stock Exchange.

What Is the Stock Symbol for Apellis Pharma?

The stock symbol for Apellis Pharma is "APLS."

What Is the Apellis Pharma Market Cap?

As of today, Apellis Pharma market cap is 2.20B USD.

What Is Apellis Pharma's Earnings Per Share (TTM)?

The Apellis Pharma EPS (TTM) is 0.17.

When Is the Next Apellis Pharma Earnings Date?

Apellis Pharma will release its next earnings report on Apr 30, 2026.

From a Technical Analysis Perspective, Is APLS a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Strong Sell.

How Many Times Has Apellis Pharma Stock Split?

Apellis Pharma has split 0 times.

How Many Employees Does Apellis Pharma Have?

Apellis Pharma has 736 employees.

What is the current trading status of Apellis Pharma (APLS)?

As of Mar 22, 2026, Apellis Pharma (APLS) is trading at a price of 17.21 USD, with a previous close of 17.97 USD. The stock has fluctuated within a day range of 17.16 USD to 18.09 USD, while its 52-week range spans from 16.10 USD to 30.48 USD.

What Is Apellis Pharma (APLS) Price Target According to Analysts?

The average 12-month price target for Apellis Pharma is 33.40 USD, with a high estimate of 55 USD and a low estimate of 18 USD. 15 analysts recommend buying the stock, while 1 suggest selling, leading to an overall rating of Buy. The stock has an +94.07% Upside potential.

What Is the APLS Premarket Price?

APLS's last pre-market stock price is 17.90 USD. The pre-market share volume is 1,790.00, and the stock has decreased by -0.07, or -0.39%.

What Is the APLS After Hours Price?

APLS's last after hours stock price is 17.55 USD, the stock has decreased by 0.34, or 1.98%.
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