Apellis Pharmaceuticals Inc (APLS)

Currency in USD
21.31
-0.82(-3.71%)
Real-time Data·
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Fair Value
Day's Range
20.9422.40
52 wk Range
16.1030.48
Key Statistics
Prev. Close
22.13
Open
22.4
Day's Range
20.94-22.4
52 wk Range
16.1-30.48
Volume
1.48M
Average Volume (3m)
2.77M
1-Year Change
-20.8178%
Book Value / Share
3.18
Fair Value
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Fair Value Upside
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APLS Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
33.58
Upside
+57.57%
Members' Sentiments
Bearish
Bullish
ProTips
5 analysts have revised their earnings upwards for the upcoming period
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Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Sell
Technical Indicators
Strong Sell
Moving Averages
Strong Sell

Apellis Pharmaceuticals Inc Company Profile

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs. It offers EMPAVELI for the treatment of paroxysmal nocturnal hemoglobinuria; and SYFOVRE for treating geographic atrophy secondary to age-related macular degeneration and geographic atrophy (GA). The company also develops EMPAVELI to treat C3 glomerulopathy and immune complex membranoproliferative glomerulonephritis, focal segmental glomerulosclerosis, and delayed graft function; and APL-3007, a small interfering RNA, or siRNA for the treatment of GA. In addition, it conducts preclinical studies for APL-9099, a treatment targeting the neonatal Fc receptor, or FcRn, which has the potential to be a first-in-class gene editing treatment for future target indications with one-time dosing; and developing other programs with its proprietary in-house capabilities and under its Beam collaboration. It has a collaboration and license agreement with Swedish Orphan Biovitrum AB (publ) for development and commercialization of pegcetacoplan; and a collaboration with Beam Therapeutics, Inc. focused on the use of Beam’s base editing technology to discover new treatments for complement-driven diseases. Apellis Pharmaceuticals, Inc. was incorporated in 2009 and is headquartered in Waltham, Massachusetts.

Employees
708

Apellis Pharmaceuticals Inc Earnings Call Summary for Q4/2025

  • Q4 2025 revenue reached $200M, exceeding forecast of $198.82M; full-year revenue hit $1B including $275M one-time payment.
  • Syfovre generated $155M and Empaveli $35M in Q4; strong product demand continues despite 6.36% pre-market stock decline to $21.04.
  • Operating expenses rose to $251M from $239M year-over-year, driven by new pivotal trials and milestone payments.
  • 2026 guidance projects modestly higher expenses; planned Syfovre prefilled syringe launch and AI-enabled OCT technology development underway.
  • Company managing $94M convertible debt maturing September 2026; maintains strong liquidity with 3.54 current ratio.
Last Updated: 2026-02-24, 09:48 a/m
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Compare APLS to Peers and Sector

Metrics to compare
APLS
Peers
Sector
Relationship
P/E Ratio
120.8x14.0x−0.6x
PEG Ratio
1.100.290.00
Price/Book
7.3x6.9x2.6x
Price / LTM Sales
2.7x7.7x3.3x
Upside (Analyst Target)
31.2%149.6%45.1%
Fair Value Upside
Unlock12.8%5.5%Unlock

Analyst Ratings

14 Buy
7 Hold
1 Sell
Ratings:
22 analysts
Overall Consensus
Buy

Analysts 12-Month Price Target:

Average 33.58
(+57.57% Upside)
Firm
ArticlePositionPrice TargetUpside / DownsideFrom Price TargetActionDate
H.C. Wainwright
Buy48.00+126.42%45.00MaintainFeb 25, 2026
Citi
Buy44.00+107.55%45.00MaintainFeb 25, 2026
Barclays
Hold24.00+13.21%-New CoverageJan 28, 2026
BofA Securities
Buy28.00+32.08%-UpgradeJan 21, 2026
Wells Fargo
Buy26.00+22.64%29.00MaintainJan 20, 2026

Earnings

Latest Release
Feb 24, 2026
EPS / Forecast
0.47 / -0.38
Revenue / Forecast
199.91M / 198.82M
EPS Revisions
Last 90 days

APLS Income Statement

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FAQ

What Is the Apellis Pharma (APLS) Stock Price Today?

The Apellis Pharma stock price today is 21.31 USD.

What Stock Exchange Does Apellis Pharma Trade On?

Apellis Pharma is listed and trades on the Nasdaq Stock Exchange.

What Is the Stock Symbol for Apellis Pharma?

The stock symbol for Apellis Pharma is "APLS."

What Is the Apellis Pharma Market Cap?

As of today, Apellis Pharma market cap is 2.73B USD.

What Is Apellis Pharma's Earnings Per Share (TTM)?

The Apellis Pharma EPS (TTM) is 0.18.

When Is the Next Apellis Pharma Earnings Date?

Apellis Pharma will release its next earnings report on Apr 30, 2026.

From a Technical Analysis Perspective, Is APLS a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Strong Sell.

How Many Times Has Apellis Pharma Stock Split?

Apellis Pharma has split 0 times.

How Many Employees Does Apellis Pharma Have?

Apellis Pharma has 708 employees.

What is the current trading status of Apellis Pharma (APLS)?

As of Feb 25, 2026, Apellis Pharma (APLS) is trading at a price of 21.31 USD, with a previous close of 22.13 USD. The stock has fluctuated within a day range of 20.94 USD to 22.40 USD, while its 52-week range spans from 16.10 USD to 30.48 USD.

What Is Apellis Pharma (APLS) Price Target According to Analysts?

The average 12-month price target for Apellis Pharma is 33.58 USD, with a high estimate of 55 USD and a low estimate of 18 USD. 14 analysts recommend buying the stock, while 1 suggest selling, leading to an overall rating of Buy. The stock has an +57.57% Upside potential.

What Is the APLS Premarket Price?

APLS's last pre-market stock price is 21.90 USD. The pre-market share volume is 610.00, and the stock has decreased by -0.23, or -1.04%.
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