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Ionis Pharmaceuticals Inc (IONS)

NASDAQ
Currency in USD
38.58
+0.47(+1.23%)
Closed
After Hours
39.21+0.63(+1.63%)
IONS Scorecard
Full Analysis
Significant return over the last week
Fair Value
Day's Range
38.5240.10
52 wk Range
33.3354.44
Key Statistics
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Prev. Close
38.11
Open
38.82
Day's Range
38.52-40.1
52 wk Range
33.33-54.44
Volume
1.87M
Average Volume (3m)
1.7M
1-Year Change
-20.76%
Book Value / Share
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Fair Value
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Fair Value Upside
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IONS Scorecardpro icon
Company’s Health
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Fair Value
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Upsidepro lock
Price Target
61.20
Upside
+58.63%
Members' Sentiments
Bearish
Bullish
ProTips
Analysts anticipate sales decline in the current year
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Ionis Pharmaceuticals Inc Company Profile

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of ATTR; Olezarsen for patients with FCS and severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Tofersen to inhibit the production of superoxide dismutase 1; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus. In addition, the company develops IONIS-FB-LRx to inhibit the production of complement factor B and the alternative complement pathway; and ION224 to reduce the production of diacylglycerol acyltransferase 2. It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with Metagenomi, Inc, AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis, Roche, Swedish Orphan Biovitrum AB, and PTC Therapeutics. The company was incorporated in 1989 and is based in Carlsbad, California.

Ionis Pharmaceuticals Inc SWOT Analysis


Pipeline Potential
Explore Ionis' late-stage candidates, including eplontersen for ATTR and donidalorsen for HAE, poised to reshape treatment paradigms in rare diseases
Financial Trajectory
Analysts project Ionis reaching EBIT trough in 2024, with multiple product launches driving revenue growth and potential cash-flow positivity by 2027
Market Opportunities
Delve into Ionis' target markets, including the vast ATTR-CM space with up to 500,000 US patients, and the underappreciated potential in SHTG
Analyst Outlook
Average price target of $60, ranging from $45 to $70, reflects optimism about Ionis' robust pipeline and upcoming catalysts amid execution risks
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Ionis Pharmaceuticals Inc Earnings Call Summary for Q1/2024

  • Positive Phase 3 data for olezarsen and donidalorsen; regulatory submissions planned in US and Europe
  • 2023 non-GAAP operating loss of $247M; revenues of $788M exceeded guidance
  • 2024 revenue projection over $575M, driven by WAINUA launch and R&D partnerships
  • Expanded Phase 3 pipeline with 9 medicines in Phase 2, targeting multibillion-dollar revenue opportunities
  • Year-end cash balance projected at $1.7B despite increased expenses; mid-single-digit increase in operating costs expected
Last Updated: 2024-02-22, 09:41 a/m
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Compare IONS to Peers and Sector

Metrics to compare
IONS
Peers
Sector
Relationship
P/E Ratio
−17.0x−7.9x−0.6x
PEG Ratio
−1.18−0.220.00
Price/Book
9.2x2.6x2.6x
Price / LTM Sales
7.6x3.5x3.2x
Upside (Analyst Target)
62.7%34.8%46.2%
Fair Value Upside
Unlock8.5%7.0%Unlock

Analysts' Recommendations

17 Buy
7 Hold
1 Sell
Ratings:
25 analysts
Overall Consensus
Buy

Analysts 12-Month Price Target:

Average 61.20

(+58.63% Upside)

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FAQ

What Is the Ionis Pharma (IONS) Stock Price Today?

The Ionis Pharma stock price today is 38.58

What Stock Exchange Does Ionis Pharma Trade On?

Ionis Pharma is listed and trades on the NASDAQ stock exchange.

What Is the Stock Symbol for Ionis Pharma?

The stock symbol for Ionis Pharma is "IONS."

What Is the Ionis Pharma Market Cap?

As of today, Ionis Pharma market cap is 6.12B.

What is Ionis Pharma Earnings Per Share?

The Ionis Pharma EPS is -2.46.

What Is the Next Ionis Pharma Earnings Date?

Ionis Pharma will release its next earnings report on Feb 19, 2025.

From a Technical Analysis Perspective, Is IONS a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Strong Buy.
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