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Iteos Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of immuno-oncology therapeutics for patients with cancer. The company’s lead antibody product candidate, belrestotug, an antagonist of TIGIT or T-cell immunoreceptor with Ig and ITIM domains, which is in Phase 1b clinical trial, as well as used to engage the Fc gamma receptor, or Fc?R to activate dendritic cells, natural killer cells, and macrophages and to promote antibody-dependent cellular cytotoxicity, or ADCC activity. Its product pipeline also includes inupadenant, a next-generation A2AR antagonists that is in Phase 1/2a clinical trials to overcome the specific adenosine-mediated immunosuppression found in tumor microenvironment; and EOS-984, a small molecule targeting equilibrative nucleoside transporter 1 (ENT1) to inhibit the immunosuppressive activity of adenosine and restore immune cell proliferation is in Phase 1 clinical trials. Iteos Therapeutics, Inc. was founded in 2011 and is headquartered in Watertown, Massachusetts.
Name | Age | Since | Title |
---|---|---|---|
Ann D. Rhoads | 58 | 2020 | Independent Director |
Michel Detheux | 57 | 2011 | President, CEO & Director |
David L. Hallal | 57 | 2018 | Independent Chairman of the Board |
Timothy Van Hauwermeiren | 51 | 2018 | Independent Director |
Gordon Freeman | - | - | Chairman of Scientific Advisory Board |
Aaron I. Davis | 45 | 2020 | Independent Director |
Tony W. Ho | 56 | 2021 | Independent Director |
Benoit Van den Eynde | - | - | Member of Scientific Advisory Board |
Matthew Vander Heiden | - | - | Member of Scientific Advisory Board |
Roberta Zappasodi | - | - | Member of Scientific Advisory Board |
Robert Iannone | 56 | 2021 | Independent Director |
Florent Ginhoux | - | - | Member of Scientific Advisory Board |
David K. Lee | - | 2023 | Independent Director |
Mark Chao | - | - | Member of Scientific Advisory Board |
Jill M. DeSimone | 68 | 2024 | Independent Director |
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