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Omeros Corporation, a clinical-stage biopharmaceutical company, discovers, develops, and commercializes small-molecule and protein therapeutics, and orphan indications targeting immunologic diseases, including complement-mediated diseases, cancers, and addictive and compulsive disorders. The company’s products under development include Narsoplimab (OMS721/MASP-2) that has completed pivotal trial for hematopoietic stem-cell transplant-associated thrombotic microangiopathy (TA-TMA); that is in Phase III clinical trial for the treatment of immunoglobulin A nephropathy (IgAN); and Phase II clinical trial to treat COVID-19. It also develops OMS1029 that is in phase I clinical trials for long-acting second-generation antibody targeting lectin pathway disorders; OMS906 that has completed phase II clinical trials for Paroxysmal nocturnal hemoglobinuria, complement 3 glomerulopathy, and other alternative pathway disorders; and OMS527 that is in phase I clinical trials for addictions and compulsive disorders, and movement disorders. In addition, the company’s products under preclinical development comprise MASP-2, a pro-inflammatory protein target for the treatment of lectin pathway disorders; MASP-3 small-molecule inhibitors for alternative pathway disorders; and Adoptive T-Cell and Chimeric Antigen Receptor (CAR) T-Cell Therapies and Immunomodulators/Immunotoxins/Cancer Vaccines for the treatment of various cancers. Omeros Corporation was incorporated in 1994 and is headquartered in Seattle, Washington.
Name | Age | Since | Title |
---|---|---|---|
Gregory A. Demopulos | 62 | 1994 | Co-Founder, Chairman, CEO & President |
Thomas J. Cable | 81 | 1995 | Lead Independent Director |
Leroy E. Hood | 82 | 2001 | Independent Director |
Peter A. Demopulos | 67 | 1995 | Director |
Arnold C. Hanish | 73 | 2012 | Independent Director |
Rajiv J. Shah | 49 | 2015 | Independent Director |
Thomas F. Bumol | 67 | 2019 | Independent Director |
Diana T. Perkinson | 69 | 2023 | Independent Director |
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