Septerna Inc (SEPN)

Currency in USD
26.45
+0.14(+0.53%)
Closed·
26.96+0.52(+1.95%)
·
SEPN is not included in our AI-picked strategies. See which stocks are.
Fair Value
Day's Range
25.2526.73
52 wk Range
4.6632.63
Key Statistics
Prev. Close
26.31
Open
25.86
Day's Range
25.25-26.73
52 wk Range
4.66-32.63
Volume
249.53K
Average Volume (3m)
301.32K
1-Year Change
313.8498%
Book Value / Share
8.53
Fair Value
unlockUnlock
Fair Value Upside
unlockUnlock
SEPN Scorecardpro icon
Company’s Health
Unlock
Fair Value
Unlock Price
Fair Price
Upside
Price Target
43.86
Upside
+65.81%
Members' Sentiments
Bearish
Bullish
ProTips
Analysts anticipate sales growth in the current year

Septerna Inc News & Analysis

Show more

Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Sell
Technical Indicators
Strong Sell
Moving Averages
Sell

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 negative allosteric modulator (NAM) for chronic spontaneous urticaria and other mast cell diseases; and TSHR Program, an oral small molecule TSHR NAM for graves’ disease and thyroid eye disease. In addition, it focuses on other therapeutic areas, including neurology, women’s health, cardiovascular disease, and respiratory disease. It has global collaboration and license agreement with Novo Nordisk to discover, develop and commercialize multiple potential oral small molecule therapies for metabolic-related diseases based on certain specified molecular targets. The company was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. Septerna, Inc. was incorporated in 2019 and is headquartered in South San Francisco, California.

Compare SEPN to Peers and Sector

Metrics to compare
SEPN
Peers
Sector
Relationship
P/E Ratio
−24.3x−9.6x−0.5x
PEG Ratio
−0.29−0.090.00
Price/Book
3.1x4.7x2.6x
Price / LTM Sales
25.8x17.9x3.2x
Upside (Analyst Target)
63.4%57.9%53.2%
Fair Value Upside
Unlock−6.1%7.6%Unlock

Analyst Ratings

8 Buy
0 Hold
0 Sell
Ratings:
8 analysts
Overall Consensus
Strong Buy

Analysts 12-Month Price Target:

Average 43.86
(+65.81% Upside)
Firm
ArticlePositionPrice TargetUpside / DownsideFrom Price TargetActionDate
Truist Securities
Buy35.00+32.33%34.00MaintainMar 10, 2026
Cantor Fitzgerald
Buy60.00+126.84%60.00MaintainMar 10, 2026
Wells Fargo
Buy48.00+81.47%28.00MaintainMar 03, 2026
H.C. Wainwright
Buy40.00+51.23%35.00MaintainMar 02, 2026
H.C. Wainwright
Buy35.00+32.33%30.00MaintainJan 20, 2026

Earnings

Latest Release
Mar 09, 2026
EPS / Forecast
-0.24 / -0.72
Revenue / Forecast
24.12M / --
EPS Revisions
Last 90 days

SEPN Income Statement

People Also Watch

51.84
MAZE
+2.78%
36.00
TYRA
-1.48%
8.330
INNV
-3.03%
14.650
ERAS
-5.48%

FAQ

What Is the Septerna (SEPN) Stock Price Today?

The Septerna stock price today is 26.45 USD.

What Stock Exchange Does Septerna Trade On?

Septerna is listed and trades on the Nasdaq Stock Exchange.

What Is the Stock Symbol for Septerna?

The stock symbol for Septerna is "SEPN."

What Is the Septerna Market Cap?

As of today, Septerna market cap is 1.19B USD.

What Is Septerna's Earnings Per Share (TTM)?

The Septerna EPS (TTM) is -1.10.

When Is the Next Septerna Earnings Date?

Septerna will release its next earnings report on May 14, 2026.

From a Technical Analysis Perspective, Is SEPN a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Sell.

How Many Times Has Septerna Stock Split?

Septerna has split 0 times.

How Many Employees Does Septerna Have?

Septerna has 130 employees.

What is the current trading status of Septerna (SEPN)?

As of Mar 13, 2026, Septerna (SEPN) is trading at a price of 26.45 USD, with a previous close of 26.31 USD. The stock has fluctuated within a day range of 25.25 USD to 26.73 USD, while its 52-week range spans from 4.66 USD to 32.63 USD.

What Is Septerna (SEPN) Price Target According to Analysts?

The average 12-month price target for Septerna is 43.86 USD, with a high estimate of 60 USD and a low estimate of 34 USD. 8 analysts recommend buying the stock, while 0 suggest selling, leading to an overall rating of Strong Buy. The stock has an +65.81% Upside potential.

What Is the SEPN After Hours Price?

SEPN's last after hours stock price is 26.96 USD, the stock has decreased by 0.52, or 1.95%.
Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers.
© 2007-2026 - Fusion Media Limited. All Rights Reserved.