- Investing.com
Barinthus Biotherapeutics plc, together with its subsidiaries, engages in the research, development, and commercialization of immunotherapies and vaccines in the United States and the United Kingdom. The company develops VTP-1000, an antigen-specific immune tolerance candidate, which is in Phase I clinical trial to restore immune non-responsiveness to gluten in patients with celiac disease; and VTP-300, an immunotherapy, which is in Phase II clinical trial for the treatment of chronic hepatitis B virus infection. It has a license agreement with Oxford University Innovation for the development and commercialization of products with thermo-responsive adjuvant scaffolds; and U.S. National Institutes of Health for the evaluation of synthetic and polymer-based vaccine technology to prevent infectious disease and treat cancer in animal models. The company was formerly known as Vaccitech plc and changed its name to Barinthus Biotherapeutics plc in November 2023. Barinthus Biotherapeutics plc was founded in 2016 and is based in Germantown, Maryland.
HBV Breakthrough | BRNS sharpens focus on Hepatitis B Virus treatments, positioning itself to address a significant unmet medical need in a competitive landscape |
Financial Challenges | Negative EPS forecasts and recent workforce reduction highlight BRNS's struggle for profitability, with cash runway extended to Q2 2026 |
Strategic Pivot | Explore BRNS's agile response to market trends, prioritizing HBV and Celiac disease research while streamlining operations |
Market Potential | Analyst price targets range from $3 to $7, reflecting varied outlooks on BRNS's ability to capitalize on its focused pipeline and industry trends |
Metrics to compare | BRNS | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipBRNSPeersSector | |
|---|---|---|---|---|
P/E Ratio | −0.4x | −1.7x | −0.5x | |
PEG Ratio | 0.07 | −0.05 | 0.00 | |
Price/Book | 0.4x | 2.0x | 2.6x | |
Price / LTM Sales | - | 6.0x | 3.2x | |
Upside (Analyst Target) | - | 209.4% | 53.4% | |
Fair Value Upside | Unlock | 20.2% | 7.7% | Unlock |