Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age and older; ALYFTREK for the treatment for people with CF 6 years of age and older; SYMDEKO/SYMKEVI for treatment of patients with CF 6 years of age and older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 month or older who have CF with ivacaftor. The company also develops CASGEVY for the treatment of sickle cell disease and transfusion-dependent beta thalassemia; JOURNAVX for the treatment of acute pain in adults; VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1/2 clinical trial; inaxaplin for the treatment of APOL1-mediated kidney disease which is in single Phase 2; VX-880 and VX-264, treatment for Type 1 Diabetes; VX-670 for the treatment of myotonic dystrophy type 1; and VX-407, a small molecule corrector for the treatment of autosomal dominant polycystic kidney disease. Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics. Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; and Entrada Therapeutics, Inc. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.
CF Market Dominance | Explore Vertex's stronghold in cystic fibrosis treatments, with an expanded treatable patient population of 94,000 across multiple regions |
Diversification Drive | Delve into Vertex's strategic expansion beyond CF, including FDA approval for Journavx in pain management and the launch of gene therapy CASGEVY |
Financial Resilience | Learn about Vertex's robust financial performance, with revenue growth of 10.06% and increased guidance for total product revenues to $10.8-$10.9 billion |
Analyst Perspectives | Discover varied analyst views on Vertex, with price targets ranging from $408 to $566, reflecting diverse opinions on the company's growth potential |
Metrics to compare | VRTX | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipVRTXPeersSector | |
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P/E Ratio | −245.6x | −0.8x | −0.5x | |
PEG Ratio | 2.14 | −0.01 | 0.00 | |
Price/Book | 8.0x | 0.9x | 2.6x | |
Price / LTM Sales | 11.9x | 3.0x | 3.0x | |
Upside (Analyst Target) | 0.6% | 207.0% | 53.8% | |
Fair Value Upside | Unlock | 20.6% | 9.6% | Unlock |