Elevation Oncology, Inc., an oncology company, focuses on the discovery and development of cancer therapies to treat patients across a range of solid tumors with significant unmet medical needs. It’s lead candidate is EO-3021, an antibody-drug conjugate (ADC) comprised of a fully human anti-Claudin 18.2 immunoglobulin G1 monoclonal antibody (mAb) site-specifically conjugated with a cleavable linker to the cytotoxic monomethyl auristatin E (MMAE) payload that is in Phase 1 clinical trial as a monotherapy and in combinations with dostarlimab, a PD-1 inhibitor, and ramucirumab, a VEGFR2 inhibitor, in patients with advanced, unresectable, or metastatic gastric/gastroesophageal junction solid tumors. The company is also developing EO-1022, an ADC containing seribantumab, a fully human immunoglobulin G2 (IgG2) anti-HER3 mAb, and an MMAE payload, with glycan site-specific conjugation for the treatment of patients with HER3-expressing solid tumors, including breast cancer, non-small cell lung cancer, and other solid tumors. It has a license agreement with CSPC Megalith Biopharmaceutical Co., Ltd. to develop and commercialize EO-3021 for the treatment of cancer. The company was formerly known as 14ner Oncology, Inc. and changed its name to Elevation Oncology, Inc. in February 2020. The company was incorporated in 2019 and is based in Boston, Massachusetts.
Promising ADC Pipeline | Elevation Oncology's lead candidate EO-3021 shows best-in-class efficacy for gastric cancers, with a 43% objective response rate in Claudin-selected patients |
Safety Advantage | EO-3021's favorable safety profile, particularly the absence of significant hematological adverse events, positions it well for potential combination therapies |
Strategic Combinations | Explore Elevation's innovative approach to combining EO-3021 with existing treatments, potentially expanding its market reach in first and second-line settings |
Financial Outlook | With a $111M cash balance and analyst price targets ranging from $6 to $7, Elevation Oncology is positioned to fund operations through key clinical milestones into 2026 |
Metrics to compare | ELEV | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipELEVPeersSector | |
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P/E Ratio | −0.3x | −3.4x | −0.5x | |
PEG Ratio | −0.03 | 0.00 | 0.00 | |
Price/Book | 0.4x | 1.8x | 2.6x | |
Price / LTM Sales | - | 25.6x | 3.0x | |
Upside (Analyst Target) | 253.4% | 230.1% | 53.7% | |
Fair Value Upside | Unlock | 3.2% | 8.4% | Unlock |