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aTyr Pharma, Inc., a biotherapeutics company, engages in the discovery and development of medicines based on novel immunological pathways in the United States. Its lead therapeutic candidate is efzofitimod, a selective modulator of NRP2 that is in Phase III clinical trial for pulmonary sarcoidosis; and in Phase 1b/2a clinical trial for treatment of other interstitial lung diseases (ILDs), such as chronic hypersensitivity pneumonitis and connective tissue disease related ILD. The company is developing ATYR0101, a fusion protein derived from a domain of aspartyl-tRNA synthetase that is in preclinical development for the treatment of fibrosis; and ATYR0750, a domain of alanyl-tRNA synthetase for the treatment of liver disorders. It has collaboration and license agreement with Kyorin Pharmaceutical Co., Ltd. for the development and commercialization of efzofitimod for ILDs in Japan. aTyr Pharma, Inc. was incorporated in 2005 and is headquartered in San Diego, California.
Name | Age | Since | Title |
---|---|---|---|
Osamu Nureki | - | 2009 | Member of Scientific Advisory Board |
Wing Hung Wong | - | - | Member of Scientific Advisory Board |
John K. Clarke | 70 | 2005 | Independent Director |
Nancy Ip | - | - | Member of Scientific Advisory Board |
Timothy J. Rink | 78 | 2011 | Member of Therapeutic Advisory Board |
Paul Negulescu | - | 2011 | Member of Therapeutic Advisory Board |
R. Alan B. Ezekowitz | 70 | - | Member of Therapeutic Advisory Board |
Sanjay S. Shukla | 52 | 2016 | President, CEO & Director |
Svetlana Lucas | 52 | 2019 | Independent Director |
Sara L. Zaknoen | 65 | 2021 | Independent Director |
Paul R. Schimmel | 83 | 2005 | Independent Director |
Benjamin F. Cravatt | 53 | - | Member of Scientific Advisory Board |
Douglas Edward Williams | 66 | 2011 | Member of Therapeutic Advisory Board |
Bruce A. Beutler | - | 2009 | Member of Scientific Advisory Board |
Leonard Patrick Gage | 82 | 2011 | Member of Therapeutic Advisory Board |
Keith James | - | 2011 | Member of Therapeutic Advisory Board |
Arthur M. Mercurio | - | 2020 | Scientific Advisor |
Timothy P. Coughlin | 57 | 2017 | Independent Chairman of the Board |
Jane A. Gross | 67 | 2019 | Independent Director |
Thomas O. Daniel | 70 | 2011 | Member of Therapeutic Advisory Board |
Wendell D. Wierenga | 76 | 2011 | Member of Therapeutic Advisory Board |
Floyd E. Bloom | 87 | 2009 | Member of Scientific Advisory Board |
Susan L. Ackerman | - | - | Member of Scientific Advisory Board |
Richard A. Heyman | 67 | 2011 | Member of Therapeutic Advisory Board |
Judith Varner | - | 2021 | Scientific Advisor |
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