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Feb 28 (Reuters) - Canada's main stock index slumped onWednesday, pulled lower by energy shares that fell alongside theprice of oil and as Valeant Pharmaceuticals (NYSE:VRX) VRX.TO tumbledafter the company gave a weaker-than-expected revenue forecast.
* The sell-off on the Toronto market accelerated into theclosing bell, following Wall Street lower and making for itsbiggest decline in nearly three weeks.
* Worries over higher interest rates dragged the benchmarkS&P 500 .SPX lower for the second day in a row after new U.S.Federal Reserve Chair Jerome Powell struck a bullish tone on thestrength of the economy on Tuesday. The Toronto Stock Exchange's S&P/TSX composite index .GSPTSE ended down 228.47 points, or 1.46 percent, at15,442.68.
* The energy sector .SPTTEN , which accounts for about athird of the index, retreated 3.4 percent as oil prices fellafter data showed a surprise drop in U.S. crude production inDecember. U.S. crude CLc1 settled down $1.37 at $61.64 abarrel. O/R
* Suncor Energy SU.TO was one of the biggest drags on theindex, shedding 3.2 percent to C$42.24, while Canadian NaturalResources CNQ.TO lost 4.1 percent to C$39.75.
* Valeant VRX.TO VRX.N slumped 11.5 percent to C$21.01after the drugmaker gave a disappointing outlook for 2018, withseveral of its major drugs facing more competition fromgenerics. Financial shares .SPTTFS also dragged the index lower,down 1.3 percent. Royal Bank of Canada RY.TO fell 1.7 percentto C$101.09, and Toronto-Dominion Bank TD.TO lost 1.7 percentto C$74.00.
* The TSX posted five new 52-week highs and 12 new lows.Across all Canadian issues, there were 18 new 52-week highs and32 new lows.
* Aurora Cannabis ACB.TO was among the most activelytraded stocks by volume, up 5.2 percent at $10.40. Volume on theTSX index was 260.27 million shares.