Denali Therapeutics Inc (DNLI)

Currency in USD
23.38
+0.36(+1.56%)
Real-time Data·
Earnings results expected in 3 days
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Fair Value
Day's Range
22.6523.46
52 wk Range
12.5827.30
Key Statistics
Prev. Close
23.02
Open
22.85
Day's Range
22.65-23.46
52 wk Range
12.58-27.3
Volume
210.1K
Average Volume (3m)
1.89M
1-Year Change
73.9583%
Book Value / Share
5.84
Fair Value
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Fair Value Upside
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DNLI Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
34.31
Upside
+46.76%
Members' Sentiments
Bearish
Bullish
ProTips
Suffers from weak gross profit margins

Denali Therapeutics Inc News & Analysis

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Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Sell
Technical Indicators
Strong Sell
Moving Averages
Sell

Analyst Ratings

19 Buy
1 Hold
0 Sell
Ratings:
20 analysts
Overall Consensus
Strong Buy

Analysts 12-Month Price Target:

Average 34.31
(+46.76% Upside)
Firm
ArticlePositionPrice TargetUpside / DownsideFrom Price TargetActionDate
Morgan Stanley
Buy36.00+53.91%35.00MaintainJul 23, 2026
Deutsche Bank
Buy35.00+49.64%31.00MaintainJul 17, 2026
JPMorgan
Buy29.00+23.98%-New CoverageJul 13, 2026
Stifel
Buy41.00+75.29%41.00MaintainJun 22, 2026
UBS
Buy25.00+6.88%25.00MaintainJun 16, 2026

Earnings

Latest Release
May 07, 2026
EPS / Forecast
-0.69 / -0.66
Revenue / Forecast
-- / 17.96M
EPS Revisions
Last 90 days

DNLI Income Statement

Compare DNLI to Peers and Sector

Metrics to compare
DNLI
Peers
Sector
Relationship
P/E Ratio
−7.2x−1.3x−0.4x
PEG Ratio
0.93−0.050.00
Price/Book
4.0x4.9x2.6x
Price / LTM Sales
-60.2x3.0x
Upside (Analyst Target)
52.0%109.5%56.0%
Fair Value Upside
Unlock16.1%9.1%Unlock

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson’s and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company’s OTV programs also comprise DNL628 targeting tau for Alzheimer’s disease; and DNL422 targeting alpha synuclein for Parkinson’s disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer’s disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

Ownership

Ownership Overview

Type
Common Stock Held% of Shares OutstandingMarket Value
Mutual Funds & ETFs
84.16M53.03%1.94B
Other Institutional Investors
85.56M46.97%1.97B
Public Companies & Retail Investors
0.000.00%0.00
Total
169.71M100.00%3.91B

Top Holders

Holder
% of holding
Shares Held
Date Reported
Value (In 1,000s)
T. Rowe Price Group, Inc.10.19%16,178,963372,440
BlackRock, Inc.8.21%13,034,434300,053

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FAQ

What Is the Denali Therapeutics (DNLI) Stock Price Today?

The Denali Therapeutics stock price today is 23.38 USD.

What Stock Exchange Does Denali Therapeutics Trade On?

Denali Therapeutics is listed and trades on the Nasdaq Stock Exchange.

What Is the Stock Symbol for Denali Therapeutics?

The stock symbol for Denali Therapeutics is "DNLI."

What Is the Denali Therapeutics Market Cap?

As of today, Denali Therapeutics market cap is 3.71B USD.

What Is Denali Therapeutics's Earnings Per Share (TTM)?

The Denali Therapeutics EPS (TTM) is -2.88.

When Is the Next Denali Therapeutics Earnings Date?

Denali Therapeutics will release its next earnings report on Aug 06, 2026.

From a Technical Analysis Perspective, Is DNLI a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Neutral.

How Many Times Has Denali Therapeutics Stock Split?

Denali Therapeutics has split 0 times.

How Many Employees Does Denali Therapeutics Have?

Denali Therapeutics has 507 employees.

What is the current trading status of Denali Therapeutics (DNLI)?

As of Aug 03, 2026, Denali Therapeutics (DNLI) is trading at a price of 23.38 USD, with a previous close of 23.02 USD. The stock has fluctuated within a day range of 22.65 USD to 23.46 USD, while its 52-week range spans from 12.58 USD to 27.30 USD.

What Is Denali Therapeutics (DNLI) Price Target According to Analysts?

The average 12-month price target for Denali Therapeutics is 34.31 USD, with a high estimate of 42 USD and a low estimate of 25 USD. 19 analysts recommend buying the stock, while 0 suggest selling, leading to an overall rating of Strong Buy. The stock has an +46.76% Upside potential.

What Is the DNLI Premarket Price?

DNLI's last pre-market stock price is 23.20 USD. The pre-market share volume is 28,090.00, and the stock has decreased by 0.18, or 0.78%.

What Is the DNLI After Hours Price?

DNLI's last after hours stock price is 23.01 USD, the stock has decreased by -0.01, or -0.04%.
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