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Gene Therapy Pionee | Solid Biosciences leads in DMD treatment with SGT-003, showing 100% microdystrophin expression and favorable safety profile in early trials |
Pipeline Expansion | Explore Solid's strategic move into Friedreich's ataxia and CPVT, diversifying its portfolio and tapping into new market opportunities |
Financial Outlook | Delve into Solid's $200M capital raise, extending cash runway to 2027, while analysts set price targets ranging from $10 to $20 |
Market Challenges | Learn how Solid navigates a competitive landscape, regulatory hurdles, and potential safety concerns in the evolving gene therapy field |
Metrics to compare | SLDB | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipSLDBPeersSector | |
|---|---|---|---|---|
P/E Ratio | −3.9x | −3.8x | −0.5x | |
PEG Ratio | −0.11 | −0.09 | 0.00 | |
Price/Book | 3.8x | 2.4x | 2.6x | |
Price / LTM Sales | - | 10.1x | 3.2x | |
Upside (Analyst Target) | 131.9% | 90.4% | 47.8% | |
Fair Value Upside | Unlock | 7.8% | 5.9% | Unlock |
Solid Biosciences Inc. develops therapies for neuromuscular and cardiac diseases in the United States. The company’s lead product candidate is SGT-003, which is in phase 1/2 for the treatment of Duchenne muscular dystrophy. It develops SGT-212 for the treatment of Friedreich's ataxia that is in phase 1b clinical trial; SGT-501 for the treatment of catecholaminergic polymorphic ventricular tachycardia that is in preclinical phase; SGT-601 the treatment of TNNT2-mediated dilated cardiomyopathy, which is in preclinical phase; SGT-401 for the treatment of BAG3-mediated dilated cardiomyopathy that is in preclinical phase; SGT-701 for treatment of rare inherited disease characterized by mutations in the RBM20 gene, which is in discovery phase; and other drugs for the treatment of cardiac and other diseases. In addition, the company is involved in developing platform technologies, including capsid libraries; genetic regulators, such as promoters, UTRs, and introns; immunomodulation technologies; manufacturing purity; and dual gene expression, a technology for packaging multiple transgenes into one capsid. The company has collaboration and license agreement with Ultragenyx Pharmaceutical Inc.; and a license agreement with the University of Washington, University of Missouri, University of Florida, and ICS Maugeri S.p.A. Solid Biosciences Inc. was incorporated in 2013 and is headquartered in Charlestown, Massachusetts.